JacqueLENS PhD

"There have always been highly capable women wanting to be scientists." Rita Colwell, PhD

Long-Term Visual Outcomes in Neovascular Age-Related Macular Degeneration Eyes With Baseline Macular Atrophy on Anti-Vascular Endothelial Growth Factor Treatment.


Journal article


Michael J. Foster, Jacqueline K. Shaia, Christopher M. Maatouk, Catherine A. Urbano, Mark T Bui, Grant L. Hom, B. L. Kuo, Rishi P. Singh, Katherine E. Talcott
Ophthalmic Surgery Lasers and Imaging Retina, 2023

Semantic Scholar DOI PubMed
Cite

Cite

APA   Click to copy
Foster, M. J., Shaia, J. K., Maatouk, C. M., Urbano, C. A., Bui, M. T., Hom, G. L., … Talcott, K. E. (2023). Long-Term Visual Outcomes in Neovascular Age-Related Macular Degeneration Eyes With Baseline Macular Atrophy on Anti-Vascular Endothelial Growth Factor Treatment. Ophthalmic Surgery Lasers and Imaging Retina.


Chicago/Turabian   Click to copy
Foster, Michael J., Jacqueline K. Shaia, Christopher M. Maatouk, Catherine A. Urbano, Mark T Bui, Grant L. Hom, B. L. Kuo, Rishi P. Singh, and Katherine E. Talcott. “Long-Term Visual Outcomes in Neovascular Age-Related Macular Degeneration Eyes With Baseline Macular Atrophy on Anti-Vascular Endothelial Growth Factor Treatment.” Ophthalmic Surgery Lasers and Imaging Retina (2023).


MLA   Click to copy
Foster, Michael J., et al. “Long-Term Visual Outcomes in Neovascular Age-Related Macular Degeneration Eyes With Baseline Macular Atrophy on Anti-Vascular Endothelial Growth Factor Treatment.” Ophthalmic Surgery Lasers and Imaging Retina, 2023.


BibTeX   Click to copy

@article{michael2023a,
  title = {Long-Term Visual Outcomes in Neovascular Age-Related Macular Degeneration Eyes With Baseline Macular Atrophy on Anti-Vascular Endothelial Growth Factor Treatment.},
  year = {2023},
  journal = {Ophthalmic Surgery Lasers and Imaging Retina},
  author = {Foster, Michael J. and Shaia, Jacqueline K. and Maatouk, Christopher M. and Urbano, Catherine A. and Bui, Mark T and Hom, Grant L. and Kuo, B. L. and Singh, Rishi P. and Talcott, Katherine E.}
}

Abstract

BACKGROUND AND OBJECTIVE This study explores the connection between macular atrophy (MA) status at baseline and best visual acuity (BVA) after 5 to 7 years of anti-vascular endothelial growth factor (anti-VEGF) injections on eyes with neovascular age-related macular degeneration (nAMD).

PATIENTS AND METHODS This retrospective study included patients with neovascular age-related macular degeneration receiving anti-VEGF injections at least twice-yearly for 5+ years at Cole Eye Institute. Analyses of variance and linear regressions explored the connection between MA status, baseline MA intensity, and 5-year BVA change.

RESULTS Of 223 included patients, 5-year BVA change was not statistically significant between MA status groups or from baseline. The population's average 7-year BVA change was -6.3 Early Treatment Diabetic Retinopathy Study letters. Type and frequency of anti-VEGF injections were comparable between MA status groups (P > .05).

CONCLUSION Regardless of MA status, 5- and 7-year BVA change lacked clinical relevance. If receiving regular treatment for 5+ years, patients with baseline MA achieve comparable visual outcomes to those without MA, with similar treatment and visit burdens. [Ophthalmic Surg Lasers Imaging Retina 2023;54(X):X-X.].